The main research mission of the Van Leeuwen lab is to use functional genomics tools to improve our understanding of how mutations can interact to produce unexpected phenotypes, and how this determines the severity of genetic traits. Our research specifically focusses on suppression interactions, in which the accumulation of secondary mutations elsewhere in the genome can compensate for the deleterious effects of the primary mutation. For human disease genes, suppressors can represent strong targets for therapeutic intervention.
We are always looking for talented postdocs and PhD students interested in high-throughput genetic analysis, with a specific focus on suppression. Please note that you should apply at least 6 months in advance of your intended start date. Although internal funding may be available, we strongly encourage all applicants to seek external sources of funding.
Requirements: A doctorate (for postdocs) or a Master’s degree (for PhD students) in biology or a related discipline is required, and a strong background in yeast genetics or functional genomics is a plus. Exceptional interest in understanding genetic interactions and a great sense of teamwork are essential.
We currently have no technician positions available.
Please send a cover letter describing why you are interested in joining our group, a CV, and contact details for 2 or more referees to Jolanda van Leeuwen: jolanda.vanleeuwen [at] unil.ch
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